Tigranation

Description
Shoot the messanger and it's disciples.

Effects
Chests only drop one item; Rarity of items aquired from chests is 50% worse. This overrides any chest item count increase (like Unlimited Chestworks) where no matter how many times the player increases the drop count of items from chests, it will still be 1.

This makes the game harder by making runs more skill-based.

Unlock Condition
Defeat a boss without equipping any items.

This does not require a specific difficulty, meaning that this is easiest to do on DHMIS difficulty.

Trivia

 * This relic's quote is a reference to the metaphoric phrase "Shooting the Messanger", used to describe blaming the bearer of bad news.
 * This relic's icon and name is a reference to Tigranes the Great, who had an infamous "Shoot the Messanger" moment.