Spongination

Description
Enemies have 100% more health.

Effects
Enemies have their TOTAL health increased by 100%, meaning that any increase in HP for enemies is also doubled.

This makes the game harder by making everything harder to kill.

Unlock Condition
Hit a non-boss enemy 25 times without killing it.

Best done on TFPJ difficulty.

Trivia

 * This relic's icon and name is a reference to a commonly used phrase in gaming "Bullet Sponge", where enemies have so much health that they are absorbing bullets like sponges.